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How to use Extraction 1 for non-intervention reviews

Extraction 1 - Data Extraction

How to use Extraction 1 for non-intervention reviews

Last updated on 24 Mar, 2026

Extraction 1 is the right choice when you're collecting numerical data against defined groups (e.g., Mean, SD, N, effect sizes across intervention arms, exposure levels, or cases). The structure is built around comparing groups, whether those are treatments, exposures, phenomena, or individual cases.

While the Extraction 1 template has fixed section headers (Identification, Methods, Population, Interventions, Outcomes), you have complete flexibility to customize fields within each section. The "Interventions" section is just a label, it can capture any type of comparison group relevant to your research question.

This guide shows you how to set up the template for different types of reviews that aren't focused on interventions.

Your review focus:

"Interventions" section becomes:

Therapy/Treatment

Intervention vs. Control

Harm/Etiology

Exposure levels

Case Series

Individual cases (Case 1, Case 2...)

Qualitative

Phenomena of interest

Diagnostic Accuracy

Index test vs. Reference standard

Prognosis

Prognostic factor groups


Example 1: Harm / Etiology review

Research question: What is the association between screen time exposure and childhood obesity?

Extraction 1 template

Example fields

Interventions (as Exposures)

High screen time
Low screen time
No screen time

Intervention details (as Exposure details)

Hours/day
Screen type
Measurement method

Outcomes

BMI
Obesity incidence
Overweight status

How it looks like in the template:

Example 1 - Interventions.pngExample 1 - Outcomes.png

How it data capture of exposures and outcomes like in the data extraction form:

Example 1 - study form.png

Example 2: Case Series

Research question: What are the clinical presentations and outcomes of rare drug reactions?

Extraction 1 template

Example fields

Interventions (as Cases)

Case (Note: During extraction you can add multiple cases using the plus button)

Intervention details (as Case details)

Age
Sex
Drug name
Dose
Duration of exposure

Outcomes

Reaction type
Severity
Time to onset
Resolution

How it looks like in the template:

Example 2 - Interventions.pngExample 2 - Outcomes.png

How it data capture of cases like in the data extraction form:

Example 2 - Study form.png


Example 3: Qualitative Review

Research question: What are patients' experiences of living with chronic pain?

Extraction 1 template

Example fields

Methods

Qualitative approach
Data collection method
Analysis method

Interventions (as Phenomena of Interest)

Chronic pain experience
Pain management strategies

Outcome (as Findings)

Findings

How it looks like in the template:

Example 3 - Methods.pngExample 3 - Intervention.pngExample 3 - Study form.png

How data capture of phenomena of interest and findings looks like in the data extraction form:

Example 3 - Study form.png

Example 4: Diagnostic Test Accuracy

Research question: What is the accuracy of rapid antigen tests for detecting COVID-19?

Extraction 1 template

Example fields

Methods

Test manufacturer
Sample type
Setting

Interventions (as Index tests)

Rapid antigen test
RT-PCR (as reference)

Intervention details (as Index test characteristics)

Brand
Sample type

Outcomes (as Target condition)

COVID-19 infection

Result data

Sensitivity
Specificity
PPV
NPV

How it looks like in the template:

Example 4 - Methods.pngExample 4 - Interventions.pngExample 4 - Outcomes.png

How data capture of index tests and target condition looks like in the data extraction form:

Example 4 - Study form.png

Example 5: Prognostic review

Research question: What factors predict recurrence in early-stage breast cancer patients?

Extraction 1 template

Example fields

Interventions (as Prognostic factors)

Factor present
Factor absent

Intervention details (as Prognostic factor details)

Factor definition
Measurement method
Cut-off value

Outcomes

Event type (e.g. recurrence, mortality)
Follow-up duration

How it looks like in the template:

Example 5 - Interventions.pngExample 5 - Outcomes.png

How data capture of prognostic factors looks like in the data extraction form:

Example 5 - Study form.png

Recommendations

Extraction 1 works for any review where you're comparing groups and collecting structured data against them.

The key is understanding how to repurpose the fixed section names (especially "Interventions") to capture the data elements relevant to your specific research question.

If your review is purely descriptive or focused on mapping evidence without group comparisons, Extraction 2 may be a better fit.

Strongly recommend Extraction 1 for:

  • Intervention/therapy reviews

  • Treatment effectiveness

  • Any review planning meta-analysis

Extraction 1 is also highly suitable for:

  • Prevention reviews

  • Harm/etiology reviews

  • Mixed methods

  • Rapid reviews with quantitative synthesis

  • Case series

  • Qualitative reviews (with customization)

  • Diagnostic accuracy (with customization)

Consider Extraction 2 instead for:

  • Scoping reviews without synthesis

  • Network meta-analysis

  • Umbrella reviews

  • Reviews requiring completely custom structures outside the Extraction 1 framework

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